{"id":7557,"date":"2021-01-09T05:44:00","date_gmt":"2021-01-09T05:44:00","guid":{"rendered":"https:\/\/by-tv.co.uk\/?p=7557"},"modified":"2021-01-09T05:44:00","modified_gmt":"2021-01-09T05:44:00","slug":"biontech-pifzer-asisi-kovid-19un-yeni-mutasyonuna-karsi-da-etkili-oldu","status":"publish","type":"post","link":"https:\/\/by-tv.co.uk\/en\/biontech-pifzer-asisi-kovid-19un-yeni-mutasyonuna-karsi-da-etkili-oldu\/","title":{"rendered":"Biontech-Pifzer a\u015f\u0131s\u0131, Kovid-19’un yeni mutasyonuna kar\u015f\u0131 da etkili oldu"},"content":{"rendered":"
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ABD’de yap\u0131lan bir ara\u015ft\u0131rma, Biontech-Pfizer a\u015f\u0131s\u0131n\u0131n yeni tip koronavir\u00fcs\u00fcn (Kovid-19) mutasyona u\u011frayarak daha h\u0131zl\u0131 yay\u0131lan t\u00fcr\u00fcne kar\u015f\u0131 da etkili oldu\u011funu ortaya koydu.<\/p>\n

ABD’li ila\u00e7 firmas\u0131 Pfizer’den yap\u0131lan a\u00e7\u0131klamada, Teksas \u00dcniversitesi T\u0131p Fak\u00fcltesi i\u015f birli\u011finde y\u00fcr\u00fct\u00fclen laboratuvar testlerinde, vir\u00fcs\u00fcn insan h\u00fccrelerine tutunmas\u0131n\u0131 sa\u011flayan “diken proteininde” meydana gelen de\u011fi\u015fikli\u011fin a\u015f\u0131n\u0131n etkisini de\u011fi\u015ftirmedi\u011fi belirtildi.<\/p>\n

A\u015f\u0131y\u0131 vurulan 20 ki\u015fiden al\u0131nan kan \u00f6rnekleriyle yap\u0131lan testlerde, vir\u00fcse kar\u015f\u0131 \u00fcretilen antikorlar\u0131n yeni mutasyonu etkisiz hale getirdi\u011fi tespit edildi. Kovid-19’un 15 farkl\u0131 mutasyonunun incelendi\u011fi ara\u015ft\u0131rmada, a\u015f\u0131n\u0131n etkinli\u011fine dair olumsuz bir durumla kar\u015f\u0131la\u015f\u0131lmad\u0131.<\/p>

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“Mutasyonun problem yaratmad\u0131\u011f\u0131n\u0131 g\u00f6rmek memnuniyet verici”\u0130ngiltere ve G\u00fcney Afrika’da ortaya \u00e7\u0131kan “N501Y” ad\u0131 verilen mutasyon, vir\u00fcs\u00fcn diken proteinin tek noktas\u0131nda ortaya \u00e7\u0131kan de\u011fi\u015fimden kaynaklan\u0131yor. S\u00f6z konusu mutasyonun vir\u00fcs\u00fcn v\u00fccuda daha kolay tutunmas\u0131n\u0131 sa\u011flad\u0131\u011f\u0131 ve b\u00f6ylece bula\u015f\u0131c\u0131l\u0131\u011f\u0131n\u0131 art\u0131rd\u0131\u011f\u0131 tahmin ediliyor.<\/p>\n

Pfizer Bilim Operasyonlar\u0131 \u00dcst Y\u00f6neticisi Dr. Philip Dormitzer, vir\u00fcste meydana gelen de\u011fi\u015fikliklerin a\u015f\u0131 \u00fczerindeki etkisine ili\u015fkin \u00e7al\u0131\u015fmalar\u0131n s\u00fcrece\u011fini belirterek “\u0130nsanlar\u0131 fazlas\u0131yla endi\u015felendiren bu mutasyonun bir problem yaratmad\u0131\u011f\u0131n\u0131 g\u00f6rmek memnuniyet verici.” ifadelerini kulland\u0131.<\/p>\n

Vir\u00fcslerin mutasyonun ba\u011fl\u0131 olarak a\u015f\u0131 form\u00fcllerinde de de\u011fi\u015fiklik yap\u0131labilece\u011fine dikkati \u00e7eken Dormitzer, RNA temelli a\u015f\u0131daki vir\u00fcse ait genetik kodu de\u011fi\u015ftirerek a\u015f\u0131n\u0131n mutasyonlara kar\u015f\u0131 uyarlanabilece\u011fini vurgulad\u0131.<\/p>\n

“E484K” mutasyonu endi\u015fe kayna\u011f\u0131Vir\u00fcs\u00fcn G\u00fcney Afrika’da ortaya \u00e7\u0131kan “E484K” mutasyonu, bilim insanlar\u0131n\u0131 endi\u015feye sevk ediyor. Pfizer’in ara\u015ft\u0131rmas\u0131nda yer almayan yeni mutasyonun, diken proteininde yeni de\u011fi\u015fimlere yol a\u00e7t\u0131\u011f\u0131 ifade ediliyor.<\/p>\n<\/div>\n

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AA<\/div>\n<\/div>\n
\"\"<\/a><\/div>","protected":false},"excerpt":{"rendered":"

ABD’de yap\u0131lan bir ara\u015ft\u0131rma, Biontech-Pfizer a\u015f\u0131s\u0131n\u0131n yeni tip koronavir\u00fcs\u00fcn (Kovid-19) mutasyona u\u011frayarak daha h\u0131zl\u0131 yay\u0131lan t\u00fcr\u00fcne kar\u015f\u0131 da etkili oldu\u011funu ortaya koydu. ABD’li ila\u00e7 firmas\u0131 Pfizer’den yap\u0131lan a\u00e7\u0131klamada, Teksas \u00dcniversitesi T\u0131p Fak\u00fcltesi i\u015f birli\u011finde y\u00fcr\u00fct\u00fclen laboratuvar testlerinde, vir\u00fcs\u00fcn insan h\u00fccrelerine tutunmas\u0131n\u0131 sa\u011flayan “diken proteininde” meydana gelen de\u011fi\u015fikli\u011fin a\u015f\u0131n\u0131n etkisini de\u011fi\u015ftirmedi\u011fi belirtildi. A\u015f\u0131y\u0131 vurulan 20 ki\u015fiden al\u0131nan kan \u00f6rnekleriyle yap\u0131lan testlerde, vir\u00fcse kar\u015f\u0131 \u00fcretilen antikorlar\u0131n yeni mutasyonu etkisiz hale getirdi\u011fi tespit edildi. Kovid-19’un 15 farkl\u0131 mutasyonunun incelendi\u011fi ara\u015ft\u0131rmada, a\u015f\u0131n\u0131n etkinli\u011fine dair olumsuz bir durumla kar\u015f\u0131la\u015f\u0131lmad\u0131. “Mutasyonun problem yaratmad\u0131\u011f\u0131n\u0131 g\u00f6rmek memnuniyet verici”\u0130ngiltere ve G\u00fcney Afrika’da ortaya \u00e7\u0131kan “N501Y” ad\u0131 verilen mutasyon, vir\u00fcs\u00fcn […]<\/p>\n","protected":false},"author":1,"featured_media":7558,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[15,11],"tags":[1834,2316,1833],"class_list":["post-7557","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ingiltere","category-dunya","tag-biontech","tag-phizer","tag-ugur-sahin"],"_links":{"self":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts\/7557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/comments?post=7557"}],"version-history":[{"count":0,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts\/7557\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/media\/7558"}],"wp:attachment":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/media?parent=7557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/categories?post=7557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/tags?post=7557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}