{"id":39148,"date":"2026-05-31T11:30:28","date_gmt":"2026-05-31T10:30:28","guid":{"rendered":"https:\/\/by-tv.co.uk\/?p=39148"},"modified":"2026-05-31T11:30:28","modified_gmt":"2026-05-31T10:30:28","slug":"kanser-asisinda-buyuk-umut-bazi-hastalarda-tumorlerin-tamami-ortadan-kalkti","status":"publish","type":"post","link":"https:\/\/by-tv.co.uk\/en\/kanser-asisinda-buyuk-umut-bazi-hastalarda-tumorlerin-tamami-ortadan-kalkti\/","title":{"rendered":"Kanser a\u015f\u0131s\u0131nda b\u00fcy\u00fck umut: Baz\u0131 hastalarda t\u00fcm\u00f6rlerin tamam\u0131 ortadan kalkt\u0131"},"content":{"rendered":"

Uluslararas\u0131 bir klinik ara\u015ft\u0131rmada test edilen yeni bir kanser ilac\u0131, ileri evre ve mevcut tedavilere yan\u0131t vermeyen baz\u0131 hastalarda t\u00fcm\u00f6rlerin tamamen ortadan kalkmas\u0131n\u0131 sa\u011flad\u0131. The Guardian\u2019\u0131n haberine g\u00f6re<\/strong>, sonu\u00e7lar d\u00fcnyan\u0131n en b\u00fcy\u00fck kanser konferanslar\u0131ndan biri olan Amerikan Klinik Onkoloji Derne\u011fi (ASCO) y\u0131ll\u0131k toplant\u0131s\u0131nda a\u00e7\u0131klanacak.<\/p>\n

Tedavi se\u00e7enekleri s\u0131n\u0131rl\u0131 hastalarda dikkat \u00e7ekici sonu\u00e7lar<\/h4>\n

Ara\u015ft\u0131rmada, kanseri yay\u0131lm\u0131\u015f veya yeniden n\u00fcksetmi\u015f ve kemoterapi ile imm\u00fcnoterapiden fayda g\u00f6rmemi\u015f 102 ba\u015f ve boyun kanseri hastas\u0131<\/strong> yer ald\u0131.<\/p>\n

Amivantamab<\/strong> adl\u0131 ila\u00e7 verilen hastalar\u0131n 43\u2019\u00fcnde t\u00fcm\u00f6rlerin k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc veya tamamen kayboldu\u011fu g\u00f6r\u00fcld\u00fc. Bunlardan 28\u2019inde belirgin t\u00fcm\u00f6r k\u00fc\u00e7\u00fclmesi kaydedilirken, 15 hastada t\u00fcm\u00f6rlerin tamamen ortadan kalkt\u0131\u011f\u0131<\/strong> bildirildi.<\/p>

\"\"<\/a><\/div>\n

Londra\u2019daki Kanser Ara\u015ft\u0131rmalar\u0131 Enstit\u00fcs\u00fc\u2019nden (ICR) Prof. Kevin Harrington<\/strong>, elde edilen sonu\u00e7lar\u0131n bu hasta grubu i\u00e7in \u201cbenzeri g\u00f6r\u00fclmemi\u015f derecede g\u00fc\u00e7l\u00fc\u201d oldu\u011funu belirtti. Harrington, mevcut tedavi se\u00e7eneklerinin son derece s\u0131n\u0131rl\u0131 oldu\u011fu hastalarda bu d\u00fczeyde fayda g\u00f6r\u00fclmesinin \u00f6nemli oldu\u011funu s\u00f6yledi.<\/p>\n

\u00dc\u00e7 farkl\u0131 mekanizmayla etki ediyor<\/h4>\n

Johnson & Johnson taraf\u0131ndan geli\u015ftirilen amivantamab, kanserle \u00fc\u00e7 farkl\u0131 yoldan m\u00fccadele ediyor. \u0130la\u00e7, t\u00fcm\u00f6r b\u00fcy\u00fcmesini destekleyen EGFR<\/strong> adl\u0131 proteini ve kanser h\u00fccrelerinin tedaviden ka\u00e7mak i\u00e7in kulland\u0131\u011f\u0131 MET<\/strong> yolunu engelliyor. Ayr\u0131ca ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin t\u00fcm\u00f6re kar\u015f\u0131 harekete ge\u00e7mesini destekliyor.<\/p>\n

Ara\u015ft\u0131rmac\u0131lar, ilac\u0131n akci\u011fer kanseri hastalar\u0131nda da benzer sonu\u00e7lar verdi\u011fini belirtti. Amivantamab halen akci\u011fer, kolorektal, beyin ve mide kanserleri dahil yakla\u015f\u0131k 60 klinik \u00e7al\u0131\u015fmada<\/strong> de\u011ferlendiriliyor.<\/p>\n

Uygulamas\u0131 daha kolay<\/h4>\n

\u0130la\u00e7, bir\u00e7ok kanser tedavisinin aksine damar yoluyla de\u011fil, deri alt\u0131na yap\u0131lan k\u00fc\u00e7\u00fck bir enjeksiyon<\/strong> \u015feklinde uygulan\u0131yor. Bu durum tedavi s\u00fcrecini h\u0131zland\u0131r\u0131rken, ayakta tedavi kliniklerinde uygulanmas\u0131n\u0131 da kolayla\u015ft\u0131r\u0131yor.<\/p>\n

\u00dc\u00e7 haftada bir verilen tedavide g\u00f6r\u00fclen yan etkilerin \u00e7o\u011funun hafif veya orta d\u00fczeyde oldu\u011fu, hastalar\u0131n y\u00fczde 10\u2019undan daha az\u0131n\u0131n yan etkiler nedeniyle tedaviyi b\u0131rakmak zorunda kald\u0131\u011f\u0131 bildirildi.<\/p>\n

Hasta deneyimi umut verdi<\/h4>\n

Ara\u015ft\u0131rmaya kat\u0131lan 56 ya\u015f\u0131ndaki Carl Walsh<\/strong>, dil kanseri te\u015fhisi ald\u0131ktan sonra kemoterapi ve imm\u00fcnoterapiden sonu\u00e7 alamad\u0131\u011f\u0131n\u0131, ard\u0131ndan deneme program\u0131na dahil edildi\u011fini s\u00f6yledi.<\/p>\n

Walsh, tedavi sonras\u0131nda konu\u015fma ve beslenme sorunlar\u0131n\u0131n b\u00fcy\u00fck \u00f6l\u00e7\u00fcde d\u00fczeldi\u011fini, g\u00fcnl\u00fck ya\u015fam\u0131na geri d\u00f6nebildi\u011fini ifade etti.<\/p>\n

\u00c7al\u0131\u015fmada ayr\u0131ca, HPV kaynakl\u0131 olmayan ba\u015f ve boyun kanserlerine odaklan\u0131ld\u0131\u011f\u0131na dikkat \u00e7ekildi. Uzmanlar, bu kanser t\u00fcrlerinin genellikle daha zor tedavi edildi\u011fini ve elde edilen sonu\u00e7lar\u0131n bu nedenle ayr\u0131 bir \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131 vurgulad\u0131.<\/p>\n

Ara\u015ft\u0131rma verilerine g\u00f6re, amivantamab kullanan hastalar tedaviye ba\u015flad\u0131ktan sonra ortalama 12,5 ay ya\u015fam s\u00fcresi<\/strong> elde etti. Uzmanlar, sonu\u00e7lar\u0131n daha geni\u015f hasta gruplar\u0131nda do\u011frulanmas\u0131 halinde kanser tedavisinde \u00f6nemli bir ilerleme sa\u011flayabilece\u011fini belirtiyor.<\/p>\n

\"\"<\/a><\/div>","protected":false},"excerpt":{"rendered":"

Uluslararas\u0131 bir klinik ara\u015ft\u0131rmada test edilen yeni bir kanser ilac\u0131, ileri evre ve mevcut tedavilere yan\u0131t vermeyen baz\u0131 hastalarda t\u00fcm\u00f6rlerin tamamen ortadan kalkmas\u0131n\u0131 sa\u011flad\u0131. The Guardian\u2019\u0131n haberine g\u00f6re, sonu\u00e7lar d\u00fcnyan\u0131n en b\u00fcy\u00fck kanser konferanslar\u0131ndan biri olan Amerikan Klinik Onkoloji Derne\u011fi (ASCO) y\u0131ll\u0131k toplant\u0131s\u0131nda a\u00e7\u0131klanacak. Tedavi se\u00e7enekleri s\u0131n\u0131rl\u0131 hastalarda dikkat \u00e7ekici sonu\u00e7lar Ara\u015ft\u0131rmada, kanseri yay\u0131lm\u0131\u015f veya yeniden n\u00fcksetmi\u015f ve kemoterapi ile imm\u00fcnoterapiden fayda g\u00f6rmemi\u015f 102 ba\u015f ve boyun kanseri hastas\u0131 yer ald\u0131. Amivantamab adl\u0131 ila\u00e7 verilen hastalar\u0131n 43\u2019\u00fcnde t\u00fcm\u00f6rlerin k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc veya tamamen kayboldu\u011fu g\u00f6r\u00fcld\u00fc. Bunlardan 28\u2019inde belirgin t\u00fcm\u00f6r k\u00fc\u00e7\u00fclmesi kaydedilirken, 15 hastada t\u00fcm\u00f6rlerin tamamen ortadan kalkt\u0131\u011f\u0131 bildirildi. Londra\u2019daki Kanser Ara\u015ft\u0131rmalar\u0131 Enstit\u00fcs\u00fc\u2019nden […]<\/p>\n","protected":false},"author":11,"featured_media":39149,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[11,13],"tags":[],"class_list":["post-39148","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya","category-saglik"],"_links":{"self":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts\/39148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/comments?post=39148"}],"version-history":[{"count":1,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts\/39148\/revisions"}],"predecessor-version":[{"id":39150,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/posts\/39148\/revisions\/39150"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/media\/39149"}],"wp:attachment":[{"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/media?parent=39148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/categories?post=39148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/by-tv.co.uk\/en\/wp-json\/wp\/v2\/tags?post=39148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}